HCSGD entry for NR2E3

1. General information

Official gene symbolNR2E3
Entrez ID10002
Gene full namenuclear receptor subfamily 2, group E, member 3
Other gene symbolsESCS PNR RNR RP37 rd7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003707Steroid hormone receptor activityIEAmolecular_function
GO:0004879Ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusTAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0007602PhototransductionTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0030522Intracellular receptor signaling pathwayTASbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.68673496070.71618386080.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0485639200
GSE13712_SHEARDown-0.0812102304
GSE13712_STATICUp0.0928289605
GSE19018Up0.1314575813
GSE19899_A1Up0.1864448200
GSE19899_A2Down-0.2183045777
PubMed_21979375_A1Down-0.2782240626
PubMed_21979375_A2Down-0.2110181639
GSE35957Up0.1600789569
GSE36640Down-0.0806745744
GSE54402Up0.0208308378
GSE9593Up0.0294212150
GSE43922Up0.1286876919
GSE24585Down-0.1394863743
GSE37065Down-0.0518174674
GSE28863_A1Down-0.0565960784
GSE28863_A2Down-0.1266590742
GSE28863_A3Up0.3119149869
GSE28863_A4Up0.0766144842
GSE48662Up0.0637455156

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.