HCSGD entry for CHAF1A
1. General information
| Official gene symbol | CHAF1A |
|---|---|
| Entrez ID | 10036 |
| Gene full name | chromatin assembly factor 1, subunit A (p150) |
| Other gene symbols | CAF-1 CAF1 CAF1B CAF1P150 P150 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003682 | Chromatin binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006260 | DNA replication | IEA | biological_process |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006335 | DNA replication-dependent nucleosome assembly | TAS | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0031497 | Chromatin assembly | IDA | biological_process |
| GO:0033186 | CAF-1 complex | IDA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0051082 | Unfolded protein binding | TAS | molecular_function |
| GO:0070087 | Chromo shadow domain binding | IPI | molecular_function |
| GO:0071778 | WINAC complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8360089358 | 0.0211315945 | 0.9999902473 | 0.2810736736 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0530385309 |
| GSE13712_SHEAR | Up | 0.0598071473 |
| GSE13712_STATIC | Down | -0.0879756771 |
| GSE19018 | Up | 0.0230498899 |
| GSE19899_A1 | Down | -0.3433973131 |
| GSE19899_A2 | Down | -1.0569223153 |
| PubMed_21979375_A1 | Down | -0.4713000136 |
| PubMed_21979375_A2 | Down | -1.2224422895 |
| GSE35957 | Down | -0.7058798663 |
| GSE36640 | Down | -2.2349780228 |
| GSE54402 | Down | -0.0799266269 |
| GSE9593 | Down | -0.3647678135 |
| GSE43922 | Up | 0.0366402501 |
| GSE24585 | Up | 0.0606969699 |
| GSE37065 | Down | -0.2918947379 |
| GSE28863_A1 | Down | -0.0777305575 |
| GSE28863_A2 | Up | 0.2134990714 |
| GSE28863_A3 | Up | 0.5264276600 |
| GSE28863_A4 | Up | 0.3133794550 |
| GSE48662 | Down | -0.7245150962 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001559 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-590-3p | MIMAT0004801 | MIRT016160 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032279 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049115 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
