HCSGD entry for OCLN
1. General information
| Official gene symbol | OCLN |
|---|---|
| Entrez ID | 100506658 |
| Gene full name | occludin |
| Other gene symbols | BLCPMG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0005911 | Cell-cell junction | IDA | cellular_component |
| GO:0005923 | Tight junction | IDA | cellular_component |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0006921 | Cellular component disassembly involved in execution phase of apoptosis | TAS | biological_process |
| GO:0008119 | Thiopurine S-methyltransferase activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0016327 | Apicolateral plasma membrane | IEA | cellular_component |
| GO:0030054 | Cell junction | IDA | cellular_component |
| GO:0030139 | Endocytic vesicle | IEA | cellular_component |
| GO:0045216 | Cell-cell junction organization | IMP | biological_process |
| GO:0046498 | S-adenosylhomocysteine metabolic process | IEA | biological_process |
| GO:0046500 | S-adenosylmethionine metabolic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7910365336 | 0.6910195813 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0593770724 |
| GSE13712_SHEAR | Down | -0.3162403415 |
| GSE13712_STATIC | Down | -0.1648106848 |
| GSE19018 | Up | 0.0075985249 |
| GSE19899_A1 | Up | 0.1612885465 |
| GSE19899_A2 | Down | -0.1804398202 |
| PubMed_21979375_A1 | Down | -0.1505638362 |
| PubMed_21979375_A2 | Up | 0.0155172855 |
| GSE35957 | Down | -0.1094746879 |
| GSE36640 | Up | 0.4203491331 |
| GSE54402 | Down | -0.1332897590 |
| GSE9593 | Up | 0.1170335451 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0825887595 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018585 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051654 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052167 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
