HCSGD entry for GJC1
1. General information
| Official gene symbol | GJC1 |
|---|---|
| Entrez ID | 10052 |
| Gene full name | gap junction protein, gamma 1, 45kDa |
| Other gene symbols | CX45 GJA7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001570 | Vasculogenesis | IEA | biological_process |
| GO:0005216 | Ion channel activity | IEA | molecular_function |
| GO:0005243 | Gap junction channel activity | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005921 | Gap junction | TAS | cellular_component |
| GO:0005922 | Connexon complex | IEA | cellular_component |
| GO:0006810 | Transport | NAS | biological_process |
| GO:0006936 | Muscle contraction | TAS | biological_process |
| GO:0007043 | Cell-cell junction assembly | TAS | biological_process |
| GO:0007154 | Cell communication | IEA | biological_process |
| GO:0007268 | Synaptic transmission | IEA TAS | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0014704 | Intercalated disc | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016264 | Gap junction assembly | TAS | biological_process |
| GO:0048468 | Cell development | IEA | biological_process |
| GO:0048738 | Cardiac muscle tissue development | IEA | biological_process |
| GO:0086014 | Atrial cardiac muscle cell action potential | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8163013829 | 0.0042070400 | 0.9999902473 | 0.1320760429 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1951971554 |
| GSE13712_SHEAR | Up | 0.2110457869 |
| GSE13712_STATIC | Down | -0.0832468257 |
| GSE19018 | Down | -0.6273568469 |
| GSE19899_A1 | Down | -0.7106225450 |
| GSE19899_A2 | Down | -1.7785633268 |
| PubMed_21979375_A1 | Down | -1.9089223697 |
| PubMed_21979375_A2 | Down | -1.9780515753 |
| GSE35957 | Down | -0.3125598024 |
| GSE36640 | Down | -1.4484923350 |
| GSE54402 | Down | -0.3436877606 |
| GSE9593 | Up | 0.2907120922 |
| GSE43922 | Down | -0.6883183128 |
| GSE24585 | Up | 0.2643346775 |
| GSE37065 | Down | -0.1840478226 |
| GSE28863_A1 | Down | -0.1168934412 |
| GSE28863_A2 | Up | 0.6711578093 |
| GSE28863_A3 | Down | -0.3255191974 |
| GSE28863_A4 | Up | 0.3564849098 |
| GSE48662 | Down | -0.1396290664 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025645 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-671-3p | MIMAT0004819 | MIRT037775 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
