HCSGD entry for IL18BP

1. General information

Official gene symbolIL18BP
Entrez ID10068
Gene full nameinterleukin 18 binding protein
Other gene symbolsIL18BPa
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0010469Regulation of receptor activityTASbiological_process
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0042007Interleukin-18 bindingIDAmolecular_function
GO:0042088T-helper 1 type immune responseIDAbiological_process
GO:0048019Receptor antagonist activityTASmolecular_function
GO:0070301Cellular response to hydrogen peroxideIEAbiological_process
GO:0071356Cellular response to tumor necrosis factorIEAbiological_process
GO:1900116Extracellular negative regulation of signal transductionTASbiological_process
GO:2000272Negative regulation of receptor activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.39348151670.92519920220.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0065162305
GSE13712_SHEARDown-0.2616433186
GSE13712_STATICUp0.1096768446
GSE19018Up0.0720809042
GSE19899_A1Up0.1020041647
GSE19899_A2Up0.0301147008
PubMed_21979375_A1Up0.0089459608
PubMed_21979375_A2Up0.1819653739
GSE35957Down-0.0059520189
GSE36640Up0.1987094217
GSE54402Down-0.0013800824
GSE9593Up0.1057354223
GSE43922Up0.0902346409
GSE24585Up0.2502735445
GSE37065Up0.2335996846
GSE28863_A1Down-0.0135814485
GSE28863_A2Up0.0785731471
GSE28863_A3Up0.1615278654
GSE28863_A4Down-0.0040873590
GSE48662Up0.0636688945

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018976MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.