HCSGD entry for RBM5


1. General information

Official gene symbolRBM5
Entrez ID10181
Gene full nameRNA binding motif protein 5
Other gene symbolsG15 LUCA15 RMB5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0000245Spliceosomal complex assemblyIDAbiological_process
GO:0000381Regulation of alternative mRNA splicing, via spliceosomeIDAbiological_process
GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0003677DNA bindingTASmolecular_function
GO:0003723RNA bindingTASmolecular_function
GO:0003729MRNA bindingIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005681Spliceosomal complexTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006396RNA processingTASbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008285Negative regulation of cell proliferationTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0043065Positive regulation of apoptotic processIDA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93669539910.06327999320.99999024730.4742576025

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0930074728
GSE13712_SHEARDown-0.0929003525
GSE13712_STATICDown-0.1155011947
GSE19018Down-0.2569284273
GSE19899_A1Down-0.3333190991
GSE19899_A2Down-0.3277953809
PubMed_21979375_A1Down-1.2352120845
PubMed_21979375_A2Down-0.3115366584
GSE35957Down-0.4012085051
GSE36640Down-0.0197578943
GSE54402Down-0.1192215158
GSE9593Down-0.2612907701
GSE43922Down-0.1947261811
GSE24585Up0.5463751447
GSE37065Down-0.0029278728
GSE28863_A1Up0.4961787360
GSE28863_A2Up0.1025575798
GSE28863_A3Down-0.1585917057
GSE28863_A4Down-0.1540979636
GSE48662Down-0.1162565983

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30a-5pMIMAT0000087MIRT028583ProteomicsFunctional MTI (Weak)18668040
hsa-miR-320bMIMAT0005792MIRT036197CLASHFunctional MTI (Weak)23622248
hsa-miR-186-5pMIMAT0000456MIRT045057CLASHFunctional MTI (Weak)23622248
hsa-miR-17-3pMIMAT0000071MIRT050746CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT050882CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.