HCSGD entry for MSLN
1. General information
| Official gene symbol | MSLN |
|---|---|
| Entrez ID | 10232 |
| Gene full name | mesothelin |
| Other gene symbols | MPF SMRP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007155 | Cell adhesion | NAS | biological_process |
| GO:0009986 | Cell surface | IEA | cellular_component |
| GO:0016020 | Membrane | NAS | cellular_component |
| GO:0031016 | Pancreas development | IEA | biological_process |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6520497208 | 0.5766759432 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1917796991 |
| GSE13712_SHEAR | Down | -0.1437399759 |
| GSE13712_STATIC | Down | -0.2182754540 |
| GSE19018 | Up | 0.2987394479 |
| GSE19899_A1 | Up | 0.0915250871 |
| GSE19899_A2 | Down | -0.2107884945 |
| PubMed_21979375_A1 | Down | -0.2433362014 |
| PubMed_21979375_A2 | Down | -0.1828812193 |
| GSE35957 | Down | -0.0838609448 |
| GSE36640 | Up | 0.1006397731 |
| GSE54402 | Down | -0.1561183535 |
| GSE9593 | Up | 0.1299067156 |
| GSE43922 | Up | 0.0348162981 |
| GSE24585 | Up | 0.1858845017 |
| GSE37065 | Up | 0.0376928180 |
| GSE28863_A1 | Down | -0.0484550842 |
| GSE28863_A2 | Up | 0.0350762990 |
| GSE28863_A3 | Up | 0.2853111968 |
| GSE28863_A4 | Up | 0.0789852621 |
| GSE48662 | Down | -0.0072050754 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019192 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
