HCSGD entry for SAP18


1. General information

Official gene symbolSAP18
Entrez ID10284
Gene full nameSin3A-associated protein, 18kDa
Other gene symbols2HOR0202 SAP18P
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000118Histone deacetylase complexTAScellular_component
GO:0000381Regulation of alternative mRNA splicing, via spliceosomeIDA IMPbiological_process
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006397MRNA processingIEAbiological_process
GO:0008380RNA splicingIEAbiological_process
GO:0016607Nuclear speckIDAcellular_component
GO:0035145Exon-exon junction complexIDAcellular_component
GO:0043065Positive regulation of apoptotic processIDAbiological_process
GO:0048025Negative regulation of mRNA splicing, via spliceosomeIDAbiological_process
GO:0061574ASAP complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02836011930.97347124730.39143508131.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.6417791478
GSE13712_SHEARDown-0.1135093806
GSE13712_STATICUp0.0505170403
GSE19018Down-0.2009977697
GSE19899_A1Up0.1109049410
GSE19899_A2Up0.2703635612
PubMed_21979375_A1Down-0.3118420665
PubMed_21979375_A2Up0.2200946859
GSE35957Up0.5844940471
GSE36640Up0.9825041160
GSE54402Up0.3161888052
GSE9593Up0.7825465466
GSE43922Up0.1356277862
GSE24585Up0.1996333976
GSE37065Up0.1002695927
GSE28863_A1Up0.0297497467
GSE28863_A2Down-0.0950882471
GSE28863_A3Up0.1896377148
GSE28863_A4Up0.0785790240
GSE48662Up0.2127623254

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-5pMIMAT0004949MIRT037310CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041858CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT043002CLASHFunctional MTI (Weak)23622248
hsa-miR-324-5pMIMAT0000761MIRT043131CLASHFunctional MTI (Weak)23622248
hsa-miR-196a-5pMIMAT0000226MIRT048161CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.