HCSGD entry for TNIP1


1. General information

Official gene symbolTNIP1
Entrez ID10318
Gene full nameTNFAIP3 interacting protein 1
Other gene symbolsABIN-1 NAF1 VAN nip40-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002755MyD88-dependent toll-like receptor signaling pathwayISSbiological_process
GO:0004843Ubiquitin-specific protease activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularTAScellular_component
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIDA IEAcellular_component
GO:0006412TranslationTASbiological_process
GO:0006952Defense responseTASbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0007159Leukocyte cell-cell adhesionIMPbiological_process
GO:0009101Glycoprotein biosynthetic processIDAbiological_process
GO:0043124Negative regulation of I-kappaB kinase/NF-kappaB signalingIDAbiological_process
GO:0045071Negative regulation of viral genome replicationTASbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0050729Positive regulation of inflammatory responseISSbiological_process
GO:0051019Mitogen-activated protein kinase bindingIDAmolecular_function
GO:0070373Negative regulation of ERK1 and ERK2 cascadeIDAbiological_process
GO:0085032Modulation by symbiont of host I-kappaB kinase/NF-kappaB cascadeIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00271541350.99338234110.14014196081.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2778423587
GSE13712_SHEARDown-0.0887702050
GSE13712_STATICUp0.0401943923
GSE19018Up0.9860975741
GSE19899_A1Up0.3089167107
GSE19899_A2Up1.4906025801
PubMed_21979375_A1Up1.6411783814
PubMed_21979375_A2Up1.1722612349
GSE35957Up0.5296062759
GSE36640Up0.9181442219
GSE54402Up0.3503298711
GSE9593Up0.2499778739
GSE43922Up0.6008955224
GSE24585Down-0.1694977492
GSE37065Up0.2542839196
GSE28863_A1Up0.0366476129
GSE28863_A2Up0.2634341506
GSE28863_A3Up0.2757629043
GSE28863_A4Down-0.1620599181
GSE48662Up0.1545903923

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-221-3pMIMAT0000278MIRT024151SequencingFunctional MTI (Weak)20371350
hsa-miR-324-3pMIMAT0000762MIRT042899CLASHFunctional MTI (Weak)23622248
hsa-miR-181a-5pMIMAT0000256MIRT047340CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.