HCSGD entry for NPM3
1. General information
| Official gene symbol | NPM3 |
|---|---|
| Entrez ID | 10360 |
| Gene full name | nucleophosmin/nucleoplasmin 3 |
| Other gene symbols | PORMIN TMEM123 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0006364 | RRNA processing | IEA | biological_process |
| GO:0009303 | RRNA transcription | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9067202424 | 0.0028882223 | 0.9999902473 | 0.1074195499 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.7062258655 |
| GSE13712_SHEAR | Down | -0.6088668889 |
| GSE13712_STATIC | Up | 0.1381564834 |
| GSE19018 | Down | -0.4124221314 |
| GSE19899_A1 | Down | -0.2705070275 |
| GSE19899_A2 | Down | -1.5604854198 |
| PubMed_21979375_A1 | Up | 0.1359310965 |
| PubMed_21979375_A2 | Down | -2.0708357664 |
| GSE35957 | Down | -1.1965105717 |
| GSE36640 | Down | -0.7804235383 |
| GSE54402 | Down | -0.0969515346 |
| GSE9593 | Down | -0.8025011244 |
| GSE43922 | Down | -0.5541813884 |
| GSE24585 | Down | -1.0466019260 |
| GSE37065 | Down | -0.3812856435 |
| GSE28863_A1 | Down | -0.2041454044 |
| GSE28863_A2 | Down | -0.0619972937 |
| GSE28863_A3 | Up | 0.1057910684 |
| GSE28863_A4 | Up | 0.2818034619 |
| GSE48662 | Down | -0.1950876528 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022521 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048670 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
