HCSGD entry for FBLN5
1. General information
Official gene symbol | FBLN5 |
---|---|
Entrez ID | 10516 |
Gene full name | fibulin 5 |
Other gene symbols | ADCL2 ARCL1A ARMD3 DANCE EVEC FIBL-5 UP50 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0001558 | Regulation of cell growth | IEA | biological_process |
GO:0004888 | Transmembrane signaling receptor activity | IEA | molecular_function |
GO:0005178 | Integrin binding | TAS | molecular_function |
GO:0005509 | Calcium ion binding | IEA | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005576 | Extracellular region | TAS | cellular_component |
GO:0005578 | Proteinaceous extracellular matrix | TAS | cellular_component |
GO:0005615 | Extracellular space | IDA IEA | cellular_component |
GO:0005737 | Cytoplasm | IDA | cellular_component |
GO:0007160 | Cell-matrix adhesion | TAS | biological_process |
GO:0007596 | Blood coagulation | IEA | biological_process |
GO:0008022 | Protein C-terminus binding | IPI | molecular_function |
GO:0016020 | Membrane | IEA | cellular_component |
GO:0030198 | Extracellular matrix organization | TAS | biological_process |
GO:0031012 | Extracellular matrix | IDA | cellular_component |
GO:0034394 | Protein localization to cell surface | IEA ISS | biological_process |
GO:0048251 | Elastic fiber assembly | IEA ISS | biological_process |
GO:0071953 | Elastic fiber | IEA ISS | cellular_component |
GO:2000121 | Regulation of removal of superoxide radicals | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.3104955435 | 0.0008879184 | 0.9999902473 | 0.0566338902 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Down | -0.1551479949 |
GSE13712_SHEAR | Down | -2.1876944626 |
GSE13712_STATIC | Down | -2.1301549885 |
GSE19018 | Down | -0.7484634664 |
GSE19899_A1 | Down | -2.1006236717 |
GSE19899_A2 | Down | -1.6775744714 |
PubMed_21979375_A1 | Down | -1.8619389935 |
PubMed_21979375_A2 | Down | -1.7701408577 |
GSE35957 | Up | 1.4258330225 |
GSE36640 | Up | 0.4728065502 |
GSE54402 | Down | -1.6168499804 |
GSE9593 | Up | 0.6368366765 |
GSE43922 | Down | -0.2039701863 |
GSE24585 | Up | 0.5194282968 |
GSE37065 | Up | 0.3572229824 |
GSE28863_A1 | Down | -0.0048917084 |
GSE28863_A2 | Down | -0.4926856230 |
GSE28863_A3 | Up | 0.0312892372 |
GSE28863_A4 | Down | -0.1289697792 |
GSE48662 | Up | 0.5600803156 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-200c-3p | MIMAT0000617 | MIRT006770 | Luciferase reporter assay//Western blot | Functional MTI | 22569286 |
hsa-miR-335-5p | MIMAT0000765 | MIRT018518 | Microarray | Functional MTI (Weak) | 18185580 |
hsa-miR-26b-5p | MIMAT0000083 | MIRT029864 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
---|---|
20816692 | Finally, given the importance of the elastic component for a long-lasting connective tissue structural and functional compliance, this study focuses also on elastin and fibulin-5 synthesis and deposition, demonstrating a close relationship between fibulin-5 and ageing |
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