HCSGD entry for DDX17
1. General information
| Official gene symbol | DDX17 |
|---|---|
| Entrez ID | 10521 |
| Gene full name | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| Other gene symbols | P72 RH70 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | IDA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0003724 | RNA helicase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0006200 | ATP catabolic process | TAS | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006396 | RNA processing | TAS | biological_process |
| GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
| GO:0008186 | RNA-dependent ATPase activity | TAS | molecular_function |
| GO:0009791 | Post-embryonic development | IEA | biological_process |
| GO:0030331 | Estrogen receptor binding | IDA | molecular_function |
| GO:0033148 | Positive regulation of intracellular estrogen receptor signaling pathway | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0072358 | Cardiovascular system development | IEA | biological_process |
| GO:2001014 | Regulation of skeletal muscle cell differentiation | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5894639641 | 0.0402098818 | 0.9999902473 | 0.3787989621 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0072323932 |
| GSE13712_SHEAR | Down | -0.1980538969 |
| GSE13712_STATIC | Down | -0.5828876412 |
| GSE19018 | Down | -0.0957497468 |
| GSE19899_A1 | Down | -0.6264280031 |
| GSE19899_A2 | Up | 0.0248338858 |
| PubMed_21979375_A1 | Down | -1.4235448897 |
| PubMed_21979375_A2 | Up | 0.0002003304 |
| GSE35957 | Down | -0.3240270229 |
| GSE36640 | Down | -0.0592875310 |
| GSE54402 | Down | -0.2187608199 |
| GSE9593 | Down | -0.0718916488 |
| GSE43922 | Down | -0.1110852717 |
| GSE24585 | Up | 0.2056730153 |
| GSE37065 | Up | 0.0141190821 |
| GSE28863_A1 | Up | 0.3225940014 |
| GSE28863_A2 | Up | 0.2530885151 |
| GSE28863_A3 | Down | -0.7741758921 |
| GSE28863_A4 | Up | 0.1803570691 |
| GSE48662 | Up | 0.4920703028 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-145-5p | MIMAT0000437 | MIRT006903 | Luciferase reporter assay//Northern blot//qRT-PCR//Western blot | Functional MTI | 22876303 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020898 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037628 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040859 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043487 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044259 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT046202 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049106 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051884 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378c | MIMAT0016847 | MIRT052829 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
