HCSGD entry for ARPC1A
1. General information
| Official gene symbol | ARPC1A |
|---|---|
| Entrez ID | 10552 |
| Gene full name | actin related protein 2/3 complex, subunit 1A, 41kDa |
| Other gene symbols | Arc40 SOP2Hs SOP2L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0015629 | Actin cytoskeleton | TAS | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | TAS | biological_process |
| GO:0030833 | Regulation of actin filament polymerization | IEA | biological_process |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7428155693 | 0.1714623685 | 0.9999902473 | 0.8013247514 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1790735288 |
| GSE13712_SHEAR | Down | -0.1033147290 |
| GSE13712_STATIC | Down | -0.2140467861 |
| GSE19018 | Up | 0.5886297126 |
| GSE19899_A1 | Down | -0.0038899866 |
| GSE19899_A2 | Up | 0.0432308996 |
| PubMed_21979375_A1 | Down | -0.1551928549 |
| PubMed_21979375_A2 | Down | -0.2621234055 |
| GSE35957 | Down | -0.5438675035 |
| GSE36640 | Down | -0.5130230906 |
| GSE54402 | Up | 0.2007471776 |
| GSE9593 | Up | 0.2591304091 |
| GSE43922 | Up | 0.0232945216 |
| GSE24585 | Up | 0.0649126938 |
| GSE37065 | Down | -0.2522145098 |
| GSE28863_A1 | Up | 0.0136811595 |
| GSE28863_A2 | Down | -0.0659327118 |
| GSE28863_A3 | Down | -0.4833773482 |
| GSE28863_A4 | Up | 0.0014917308 |
| GSE48662 | Down | -0.6498636146 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-423-5p | MIMAT0004748 | MIRT038032 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7i-5p | MIMAT0000415 | MIRT046551 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
