HCSGD entry for POLR3G


1. General information

Official gene symbolPOLR3G
Entrez ID10622
Gene full namepolymerase (RNA) III (DNA directed) polypeptide G (32kD)
Other gene symbolsRPC32 RPC7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003899DNA-directed RNA polymerase activityIEAmolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005666DNA-directed RNA polymerase III complexTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006359Regulation of transcription from RNA polymerase III promoterTASbiological_process
GO:0006383Transcription from RNA polymerase III promoterTASbiological_process
GO:0006385Transcription elongation from RNA polymerase III promoterTASbiological_process
GO:0006386Termination of RNA polymerase III transcriptionTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0032481Positive regulation of type I interferon productionTASbiological_process
GO:0032728Positive regulation of interferon-beta productionIMPbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045089Positive regulation of innate immune responseIMPbiological_process
GO:0051607Defense response to virusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07126579160.13807525930.56923049150.7156910004

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0473283793
GSE13712_SHEARUp2.4885946478
GSE13712_STATICUp2.4109020134
GSE19018Up0.4310047136
GSE19899_A1Up0.0488218919
GSE19899_A2Down-0.5844082938
PubMed_21979375_A1Up0.6069050139
PubMed_21979375_A2Down-0.5528464016
GSE35957Down-0.0230511146
GSE36640Down-0.7430665550
GSE54402Up0.1158308028
GSE9593Down-0.5786664063
GSE43922Down-0.2448187388
GSE24585Down-0.3077568326
GSE37065Down-0.2139856184
GSE28863_A1Down-0.0858848946
GSE28863_A2Up0.2353256345
GSE28863_A3Down-0.1513674425
GSE28863_A4Up0.1183049928
GSE48662Down-0.3260646543

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT002588MicroarrayFunctional MTI (Weak)15685193
hsa-miR-26b-5pMIMAT0000083MIRT029218SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT029218MicroarrayFunctional MTI (Weak)19088304
hsa-let-7b-5pMIMAT0000063MIRT052000CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.