HCSGD entry for GNB5


1. General information

Official gene symbolGNB5
Entrez ID10681
Gene full nameguanine nucleotide binding protein (G protein), beta 5
Other gene symbolsGB5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003924GTPase activityNASmolecular_function
GO:0004871Signal transducer activityNASmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006184GTP catabolic processNASbiological_process
GO:0007165Signal transductionNASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0008152Metabolic processNASbiological_process
GO:0016056Rhodopsin mediated signaling pathwayTASbiological_process
GO:0022400Regulation of rhodopsin mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.65669841190.31488876560.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0242343600
GSE13712_SHEARUp0.1822927868
GSE13712_STATICUp0.1203456319
GSE19018Up0.1638458006
GSE19899_A1Down-0.3026655410
GSE19899_A2Down-0.4135083726
PubMed_21979375_A1Up0.2119269620
PubMed_21979375_A2Down-0.6327048925
GSE35957Up0.0845651090
GSE36640Up0.3793506121
GSE54402Down-0.0767377297
GSE9593Up0.3415187918
GSE43922Down-0.1071476956
GSE24585Up0.1719425026
GSE37065Up0.0918457495
GSE28863_A1Up0.0453561683
GSE28863_A2Down-0.2440065727
GSE28863_A3Up0.0569048715
GSE28863_A4Down-0.1822536664
GSE48662Down-0.1794068818

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-130b-3pMIMAT0000691MIRT020117SequencingFunctional MTI (Weak)20371350
hsa-miR-128-3pMIMAT0000424MIRT021914SequencingFunctional MTI (Weak)20371350
hsa-miR-148a-3pMIMAT0000243MIRT025993SequencingFunctional MTI (Weak)20371350
hsa-miR-27a-3pMIMAT0000084MIRT028691SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT028825MicroarrayFunctional MTI (Weak)19088304
hsa-miR-425-5pMIMAT0003393MIRT039346CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.