HCSGD entry for USP20

1. General information

Official gene symbolUSP20
Entrez ID10868
Gene full nameubiquitin specific peptidase 20
Other gene symbolsLSFR3A VDU2 hVDU2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001664G-protein coupled receptor bindingIPImolecular_function
GO:0004197Cysteine-type endopeptidase activityIMPmolecular_function
GO:0004221Ubiquitin thiolesterase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005813CentrosomeIDAcellular_component
GO:0006511Ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0006897EndocytosisIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008277Regulation of G-protein coupled receptor protein signaling pathwayIMPbiological_process
GO:0016579Protein deubiquitinationIDAbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0070536Protein K63-linked deubiquitinationIDAbiological_process
GO:0071108Protein K48-linked deubiquitinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01712414800.98692148090.32240071381.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3082740299
GSE13712_SHEARDown-0.2141185528
GSE13712_STATICUp0.1476562294
GSE19018Down-0.0634973192
GSE19899_A1Up0.4513352285
GSE19899_A2Up0.8126525653
PubMed_21979375_A1Up0.3211384972
PubMed_21979375_A2Up1.5482927298
GSE35957Up0.1413757521
GSE36640Up0.5270703070
GSE54402Up0.1681814876
GSE9593Up0.4484611276
GSE43922Up0.4550222678
GSE24585Down-0.0633264596
GSE37065Down-0.0506842814
GSE28863_A1Up0.3234507880
GSE28863_A2Up0.1877929044
GSE28863_A3Up0.0018741332
GSE28863_A4Up0.0137653001
GSE48662Up0.3019651425

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT030042MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.