HCSGD entry for EHD1

1. General information

Official gene symbolEHD1
Entrez ID10938
Gene full nameEH-domain containing 1
Other gene symbolsH-PAST HPAST1 PAST PAST1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003924GTPase activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005769Early endosomeIEAcellular_component
GO:0005811Lipid particleIEA ISScellular_component
GO:0005886Plasma membraneIEA ISScellular_component
GO:0006886Intracellular protein transportIMPbiological_process
GO:0006897EndocytosisIEA IMPbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0010008Endosome membraneISS TAScellular_component
GO:0010886Positive regulation of cholesterol storageIEA ISSbiological_process
GO:0016197Endosomal transportIEAbiological_process
GO:0017137Rab GTPase bindingIPImolecular_function
GO:0030139Endocytic vesicleIEAcellular_component
GO:0031095Platelet dense tubular network membraneIEA ISScellular_component
GO:0031175Neuron projection developmentISSbiological_process
GO:0031901Early endosome membraneIDAcellular_component
GO:0032456Endocytic recyclingIGI IMPbiological_process
GO:0034383Low-density lipoprotein particle clearanceIEA ISSbiological_process
GO:0042632Cholesterol homeostasisIEA ISSbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0051260Protein homooligomerizationIPIbiological_process
GO:0055038Recycling endosome membraneIDAcellular_component
GO:1901741Positive regulation of myoblast fusionIEA ISSbiological_process
GO:1990090Cellular response to nerve growth factor stimulusISSbiological_process
GO:2001137Positive regulation of endocytic recyclingIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09058866680.79204830740.63296636581.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1061356826
GSE13712_SHEARUp0.0056567598
GSE13712_STATICUp0.2521295276
GSE19018Down-0.3210841479
GSE19899_A1Down-0.1113344910
GSE19899_A2Up0.8050903663
PubMed_21979375_A1Up1.1013656532
PubMed_21979375_A2Up0.6940088932
GSE35957Down-0.0189605965
GSE36640Up0.1279236386
GSE54402Up0.3392398749
GSE9593Up0.0152219577
GSE43922Up0.0414131157
GSE24585Down-0.0871111893
GSE37065Up0.0951421200
GSE28863_A1Up0.1882080294
GSE28863_A2Down-0.0185687009
GSE28863_A3Up0.0548227650
GSE28863_A4Up0.2014509493
GSE48662Down-0.1870978990

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT005094MicroarrayFunctional MTI (Weak)19193853
hsa-miR-34a-5pMIMAT0000255MIRT025296ProteomicsFunctional MTI (Weak)21566225
hsa-miR-7-5pMIMAT0000252MIRT025718MicroarrayFunctional MTI (Weak)17612493
hsa-miR-7-5pMIMAT0000252MIRT025718MicroarrayFunctional MTI (Weak)19073608
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.