HCSGD entry for POP1
1. General information
| Official gene symbol | POP1 |
|---|---|
| Entrez ID | 10940 |
| Gene full name | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000171 | Ribonuclease MRP activity | IDA | molecular_function |
| GO:0000172 | Ribonuclease MRP complex | IDA | cellular_component |
| GO:0001682 | TRNA 5'-leader removal | IEA | biological_process |
| GO:0004526 | Ribonuclease P activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005655 | Nucleolar ribonuclease P complex | IDA | cellular_component |
| GO:0016078 | TRNA catabolic process | IDA | biological_process |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | IDA | biological_process |
| GO:0090501 | RNA phosphodiester bond hydrolysis | IDA | biological_process |
| GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3814012234 | 0.0321769766 | 0.9999902473 | 0.3376855719 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0346112669 |
| GSE13712_SHEAR | Up | 0.7054254575 |
| GSE13712_STATIC | Up | 0.8870925768 |
| GSE19018 | Down | -1.2677568354 |
| GSE19899_A1 | Up | 0.0966186633 |
| GSE19899_A2 | Up | 0.0426402461 |
| PubMed_21979375_A1 | Up | 0.4920000655 |
| PubMed_21979375_A2 | Down | -0.0638710616 |
| GSE35957 | Down | -0.3836544330 |
| GSE36640 | Down | -1.0307158741 |
| GSE54402 | Up | 0.3523323147 |
| GSE9593 | Down | -0.4098869873 |
| GSE43922 | Up | 0.4188091769 |
| GSE24585 | Down | -0.6388111039 |
| GSE37065 | Down | -0.2391025717 |
| GSE28863_A1 | Down | -0.1983130186 |
| GSE28863_A2 | Up | 0.0110453109 |
| GSE28863_A3 | Down | -0.6729848316 |
| GSE28863_A4 | Down | -0.0054605738 |
| GSE48662 | Down | -0.6969598454 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025418 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032295 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-320a | MIMAT0000510 | MIRT044722 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
