HCSGD entry for ATE1
1. General information
| Official gene symbol | ATE1 |
|---|---|
| Entrez ID | 11101 |
| Gene full name | arginyltransferase 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004057 | Arginyltransferase activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0016598 | Protein arginylation | IEA NAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1702123855 | 0.8725881767 | 0.8117868273 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0428441399 |
| GSE13712_SHEAR | Up | 0.0480878539 |
| GSE13712_STATIC | Down | -0.0692817908 |
| GSE19018 | Down | -0.0081635952 |
| GSE19899_A1 | Up | 0.1781091924 |
| GSE19899_A2 | Up | 0.1475890814 |
| PubMed_21979375_A1 | Up | 0.5097441794 |
| PubMed_21979375_A2 | Up | 0.1150234945 |
| GSE35957 | Up | 0.1485276541 |
| GSE36640 | Up | 0.0899048339 |
| GSE54402 | Up | 0.4258282368 |
| GSE9593 | Down | -0.0035779252 |
| GSE43922 | Up | 0.2111863685 |
| GSE24585 | Up | 0.4080760028 |
| GSE37065 | Down | -0.0034907584 |
| GSE28863_A1 | Down | -0.1350059329 |
| GSE28863_A2 | Up | 0.1412493765 |
| GSE28863_A3 | Down | -0.9802803722 |
| GSE28863_A4 | Up | 0.1964353277 |
| GSE48662 | Up | 0.0081913700 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018958 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020247 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051987 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26285879 | Correlated Measurement of Endogenous ATE1 Activity on Native Acceptor Proteins in Tissues and Cultured Cells to Detect Cellular Aging |
| 26285879 | We employed cell- and tissue-based assays to detect both the level of acceptor proteins and the level of ATE1 activity under different conditions |
| 26285879 | Remarkably, in these assays, we found a close correlation between arginylation and aging, a discovery that we believe has longer-term implications in uncovering the importance of ATE1 in normal biology and disease therapies |
| 26285879 | Here we describe the original methods we used to measure ATE1 activity in tissues and correlate it with key biological events |
Entries Per Page
Displaying Page of
