HCSGD entry for PRDM4
1. General information
| Official gene symbol | PRDM4 |
|---|---|
| Entrez ID | 11108 |
| Gene full name | PR domain containing 4 |
| Other gene symbols | PFM1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008168 | Methyltransferase activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | TAS | molecular_function |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0045786 | Negative regulation of cell cycle | TAS | biological_process |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1739311424 | 0.6206792903 | 0.8191164072 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5284228674 |
| GSE13712_SHEAR | Up | 0.1371734147 |
| GSE13712_STATIC | Up | 0.0542454653 |
| GSE19018 | Down | -0.0020099689 |
| GSE19899_A1 | Down | -0.1499930222 |
| GSE19899_A2 | Up | 0.4457062374 |
| PubMed_21979375_A1 | Up | 0.7758488144 |
| PubMed_21979375_A2 | Up | 0.5310984397 |
| GSE35957 | Down | -0.3434163409 |
| GSE36640 | Down | -0.2287772489 |
| GSE54402 | Up | 0.4992206863 |
| GSE9593 | Up | 0.2844630412 |
| GSE43922 | Up | 0.0008741771 |
| GSE24585 | Down | -0.2033251266 |
| GSE37065 | Up | 0.1288774162 |
| GSE28863_A1 | Up | 0.0812605053 |
| GSE28863_A2 | Up | 0.1280496808 |
| GSE28863_A3 | Down | -0.6823818233 |
| GSE28863_A4 | Up | 0.0961626036 |
| GSE48662 | Down | -0.5143851150 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024430 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026161 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027024 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027471 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031524 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052284 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
