HCSGD entry for PKIG


1. General information

Official gene symbolPKIG
Entrez ID11142
Gene full nameprotein kinase (cAMP-dependent, catalytic) inhibitor gamma
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0004862CAMP-dependent protein kinase inhibitor activityIEAmolecular_function
GO:0007165Signal transductionIEAbiological_process
GO:0042308Negative regulation of protein import into nucleusIEAbiological_process
GO:0071901Negative regulation of protein serine/threonine kinase activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15700939550.36488831350.78657105061.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0609526021
GSE13712_SHEARDown-0.1647359131
GSE13712_STATICDown-0.4516485225
GSE19018Up0.6579924144
GSE19899_A1Down-0.8797615654
GSE19899_A2Up0.3190500418
PubMed_21979375_A1Up0.8377516705
PubMed_21979375_A2Down-0.1348471047
GSE35957Up0.1579720389
GSE36640Up1.1041287066
GSE54402Down-0.4806673960
GSE9593Up0.1404979704
GSE43922Up0.0546773499
GSE24585Down-0.1101966781
GSE37065Up0.0790788186
GSE28863_A1Up0.2964878758
GSE28863_A2Up0.4082989489
GSE28863_A3Up0.0769908652
GSE28863_A4Down-0.0021823438
GSE48662Down-0.1922406692

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-331-5pMIMAT0004700MIRT038181CLASHFunctional MTI (Weak)23622248
hsa-miR-331-3pMIMAT0000760MIRT043316CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.