HCSGD entry for CHIT1
1. General information
| Official gene symbol | CHIT1 |
|---|---|
| Entrez ID | 1118 |
| Gene full name | chitinase 1 (chitotriosidase) |
| Other gene symbols | CHI3 CHIT CHITD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000272 | Polysaccharide catabolic process | IEA | biological_process |
| GO:0004568 | Chitinase activity | IEA TAS | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005615 | Extracellular space | IC IDA | cellular_component |
| GO:0005764 | Lysosome | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | IEA | biological_process |
| GO:0006032 | Chitin catabolic process | IDA IEA TAS | biological_process |
| GO:0006955 | Immune response | NAS | biological_process |
| GO:0008061 | Chitin binding | IEA TAS | molecular_function |
| GO:0008843 | Endochitinase activity | IDA | molecular_function |
| GO:0009617 | Response to bacterium | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5510511607 | 0.9355190988 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0218477782 |
| GSE13712_SHEAR | Down | -0.0095258815 |
| GSE13712_STATIC | Down | -0.0291927878 |
| GSE19018 | Up | 0.1521309621 |
| GSE19899_A1 | Up | 0.0342058125 |
| GSE19899_A2 | Up | 0.0467714122 |
| PubMed_21979375_A1 | Down | -0.0555276000 |
| PubMed_21979375_A2 | Up | 0.1966555549 |
| GSE35957 | Up | 0.2135521351 |
| GSE36640 | Up | 0.0027254242 |
| GSE54402 | Up | 0.1762188917 |
| GSE9593 | Down | -0.0721312478 |
| GSE43922 | Up | 0.0629294744 |
| GSE24585 | Up | 0.0300508648 |
| GSE37065 | Down | -0.0356553732 |
| GSE28863_A1 | Down | -0.0238807988 |
| GSE28863_A2 | Up | 0.0639298860 |
| GSE28863_A3 | Up | 0.1839074631 |
| GSE28863_A4 | Up | 0.0359193234 |
| GSE48662 | Up | 0.0294508289 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Isopropyl Alcohol | DB02325 | EXPT01912 | DB04402 |
| N-Acetyl-D-Allosamine | DB03109 | EXPT02281 |
| 2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose | DB03539 | EXPT02280 |
| Argifin | DB03632 | EXPT02754 |
| Argadin | DB04350 | EXPT02785 |
| Allosamizoline | DB04404 | EXPT00509 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
