HCSGD entry for FZD10
1. General information
| Official gene symbol | FZD10 |
|---|---|
| Entrez ID | 11211 |
| Gene full name | frizzled family receptor 10 |
| Other gene symbols | CD350 FZ-10 Fz10 FzE7 hFz10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001944 | Vasculature development | IBA | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IBA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007420 | Brain development | IBA | biological_process |
| GO:0008406 | Gonad development | IBA | biological_process |
| GO:0009790 | Embryo development | IBA | biological_process |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0017147 | Wnt-protein binding | IBA | molecular_function |
| GO:0030165 | PDZ domain binding | IBA | molecular_function |
| GO:0030182 | Neuron differentiation | ISS | biological_process |
| GO:0032855 | Positive regulation of Rac GTPase activity | IMP | biological_process |
| GO:0032956 | Regulation of actin cytoskeleton organization | IMP | biological_process |
| GO:0034259 | Negative regulation of Rho GTPase activity | IMP | biological_process |
| GO:0038031 | Non-canonical Wnt signaling pathway via JNK cascade | IMP | biological_process |
| GO:0042813 | Wnt-activated receptor activity | IBA | molecular_function |
| GO:0042995 | Cell projection | IBA | cellular_component |
| GO:0043507 | Positive regulation of JUN kinase activity | IMP | biological_process |
| GO:0060070 | Canonical Wnt signaling pathway | IBA | biological_process |
| GO:0071300 | Cellular response to retinoic acid | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4974841457 | 0.7622955169 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1978803501 |
| GSE13712_SHEAR | Down | -0.1150169152 |
| GSE13712_STATIC | Down | -0.1158147671 |
| GSE19018 | Up | 0.1597016513 |
| GSE19899_A1 | Up | 0.1112541110 |
| GSE19899_A2 | Up | 0.0464358179 |
| PubMed_21979375_A1 | Down | -0.2338510879 |
| PubMed_21979375_A2 | Down | -0.1825164049 |
| GSE35957 | Up | 0.2164249576 |
| GSE36640 | Down | -0.0755045824 |
| GSE54402 | Up | 0.0317934145 |
| GSE9593 | Up | 0.1126456285 |
| GSE43922 | Up | 0.0353285522 |
| GSE24585 | Up | 0.1572370233 |
| GSE37065 | Down | -0.0520727442 |
| GSE28863_A1 | Up | 0.0152390686 |
| GSE28863_A2 | Up | 0.1549239274 |
| GSE28863_A3 | Up | 0.4159054693 |
| GSE28863_A4 | Up | 0.1443670991 |
| GSE48662 | Down | -0.1436441227 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017968 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027638 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
