HCSGD entry for CHN1
1. General information
| Official gene symbol | CHN1 |
|---|---|
| Entrez ID | 1123 |
| Gene full name | chimerin 1 |
| Other gene symbols | ARHGAP2 CHN DURS2 NC RHOGAP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005070 | SH3/SH2 adaptor activity | TAS | molecular_function |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0008045 | Motor neuron axon guidance | IEA ISS | biological_process |
| GO:0009967 | Positive regulation of signal transduction | TAS | biological_process |
| GO:0032314 | Regulation of Rac GTPase activity | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0046875 | Ephrin receptor binding | IEA | molecular_function |
| GO:0048013 | Ephrin receptor signaling pathway | IEA ISS | biological_process |
| GO:0050770 | Regulation of axonogenesis | IEA ISS | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9863335816 | 0.0011188823 | 0.9999902473 | 0.0634700431 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5546885468 |
| GSE13712_SHEAR | Down | -0.8291137462 |
| GSE13712_STATIC | Down | -0.1724077219 |
| GSE19018 | Up | 0.3666097788 |
| GSE19899_A1 | Down | -0.5735902681 |
| GSE19899_A2 | Down | -1.4064552491 |
| PubMed_21979375_A1 | Down | -2.7232439769 |
| PubMed_21979375_A2 | Down | -0.8863266517 |
| GSE35957 | Down | -0.9574619410 |
| GSE36640 | Up | 0.0053641747 |
| GSE54402 | Down | -1.0516428278 |
| GSE9593 | Down | -0.7259626906 |
| GSE43922 | Down | -0.3278572744 |
| GSE24585 | Up | 0.0236382086 |
| GSE37065 | Down | -0.4953854831 |
| GSE28863_A1 | Down | -0.4320848610 |
| GSE28863_A2 | Up | 0.1697163030 |
| GSE28863_A3 | Down | -0.0067502669 |
| GSE28863_A4 | Down | -0.3449412360 |
| GSE48662 | Up | 0.1133874461 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1301-3p | MIMAT0005797 | MIRT036041 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049652 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
