HCSGD entry for CHRM2

1. General information

Official gene symbolCHRM2
Entrez ID1129
Gene full namecholinergic receptor, muscarinic 2
Other gene symbolsHM2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007188Adenylate cyclase-modulating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007207Phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0008016Regulation of heart contractionIEAbiological_process
GO:0009615Response to virusIEPbiological_process
GO:0016907G-protein coupled acetylcholine receptor activityIEAmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99198984080.00011550090.99999024730.0193120253

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1094710444
GSE13712_SHEARUp0.0784343410
GSE13712_STATICDown-0.1505543799
GSE19018Down-0.1043337904
GSE19899_A1Down-0.6747883492
GSE19899_A2Down-3.4701498367
PubMed_21979375_A1Down-6.4402102875
PubMed_21979375_A2Down-1.8688273329
GSE35957Up0.1170681994
GSE36640Down-0.3438405182
GSE54402Down-4.3395088942
GSE9593Up0.0169005432
GSE43922Down-4.6112323900
GSE24585Up0.0097775228
GSE37065Down-0.0234423834
GSE28863_A1Down-0.2263021996
GSE28863_A2Down-0.6170076700
GSE28863_A3Up0.1335186301
GSE28863_A4Down-0.0263986081
GSE48662Down-0.0701264604

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017560MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.