HCSGD entry for OSBPL8
1. General information
| Official gene symbol | OSBPL8 |
|---|---|
| Entrez ID | 114882 |
| Gene full name | oxysterol binding protein-like 8 |
| Other gene symbols | MST120 MSTP120 ORP8 OSBP10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0006869 | Lipid transport | IEA | biological_process |
| GO:0010891 | Negative regulation of sequestering of triglyceride | IDA | biological_process |
| GO:0015485 | Cholesterol binding | IDA | molecular_function |
| GO:0030336 | Negative regulation of cell migration | IEA | biological_process |
| GO:0031965 | Nuclear membrane | IEA | cellular_component |
| GO:0045444 | Fat cell differentiation | IDA | biological_process |
| GO:0046628 | Positive regulation of insulin receptor signaling pathway | IEA | biological_process |
| GO:0051897 | Positive regulation of protein kinase B signaling | IEA | biological_process |
| GO:0090204 | Protein localization to nuclear pore | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0080108583 | 0.9735268721 | 0.2322178414 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1102119024 |
| GSE13712_SHEAR | Up | 0.0711008508 |
| GSE13712_STATIC | Up | 0.0209785251 |
| GSE19018 | Up | 0.0356820876 |
| GSE19899_A1 | Up | 0.6938857721 |
| GSE19899_A2 | Up | 0.3064269900 |
| PubMed_21979375_A1 | Up | 1.3945395108 |
| PubMed_21979375_A2 | Up | 1.0879244655 |
| GSE35957 | Up | 1.3146197018 |
| GSE36640 | Down | -0.0690974876 |
| GSE54402 | Up | 0.2944857229 |
| GSE9593 | Up | 0.4498212880 |
| GSE43922 | Up | 0.3256449214 |
| GSE24585 | Up | 0.1726106625 |
| GSE37065 | Up | 0.1804374135 |
| GSE28863_A1 | Up | 0.4601574068 |
| GSE28863_A2 | Up | 0.5964897552 |
| GSE28863_A3 | Down | -0.5638253680 |
| GSE28863_A4 | Up | 0.1560956144 |
| GSE48662 | Down | -0.5705067095 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002590 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002590 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-375 | MIMAT0000728 | MIRT019760 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT021770 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024824 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025706 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026213 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028261 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028471 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045443 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181b-5p | MIMAT0000257 | MIRT047291 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049706 | CLASH//Luciferase reporter assay | Functional MTI | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
