HCSGD entry for MARCH3
1. General information
| Official gene symbol | MARCH3 |
|---|---|
| Entrez ID | 115123 |
| Gene full name | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase |
| Other gene symbols | MARCH-III RNF173 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005764 | Lysosome | IDA | cellular_component |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0030659 | Cytoplasmic vesicle membrane | IEA | cellular_component |
| GO:0031901 | Early endosome membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0017834961 | 0.9882034003 | 0.1123130952 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3161478630 |
| GSE13712_SHEAR | Down | -0.1861363820 |
| GSE13712_STATIC | Down | -0.0598394655 |
| GSE19018 | Up | 0.1347928336 |
| GSE19899_A1 | Up | 1.1212034126 |
| GSE19899_A2 | Up | 1.3795776064 |
| PubMed_21979375_A1 | Up | 1.7050509778 |
| PubMed_21979375_A2 | Up | 0.9303170080 |
| GSE35957 | Up | 0.8062793793 |
| GSE36640 | Down | -0.3448835684 |
| GSE54402 | Up | 0.5872154310 |
| GSE9593 | Up | 0.0558081053 |
| GSE43922 | Up | 1.9447042399 |
| GSE24585 | Up | 0.5372957692 |
| GSE37065 | Up | 0.6884889076 |
| GSE28863_A1 | Up | 0.1111427392 |
| GSE28863_A2 | Up | 0.4872430674 |
| GSE28863_A3 | Up | 0.0016297071 |
| GSE28863_A4 | Up | 0.1487062507 |
| GSE48662 | Down | -0.2282349923 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028807 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037720 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
