HCSGD entry for SLC22A12

1. General information

Official gene symbolSLC22A12
Entrez ID116085
Gene full namesolute carrier family 22 (organic anion/urate transporter), member 12
Other gene symbolsOAT4L RST URAT1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneIDA TAScellular_component
GO:0015143Urate transmembrane transporter activityIDA IEAmolecular_function
GO:0015747Urate transportIDA IEAbiological_process
GO:0015849Organic acid transportIDAbiological_process
GO:0016021Integral component of membraneIDA IEAcellular_component
GO:0016324Apical plasma membraneIDAcellular_component
GO:0019725Cellular homeostasisNASbiological_process
GO:0022857Transmembrane transporter activityIEAmolecular_function
GO:0030165PDZ domain bindingIPImolecular_function
GO:0031526Brush border membraneIEA ISS NAScellular_component
GO:0042493Response to drugIDAbiological_process
GO:0046415Urate metabolic processIMPbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73727977660.55689632230.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2117225141
GSE13712_SHEARDown-0.1885015038
GSE13712_STATICUp0.1738070286
GSE19018Up0.0481891749
GSE19899_A1Up0.1006508114
GSE19899_A2Down-0.1934693036
PubMed_21979375_A1Down-0.0649727990
PubMed_21979375_A2Down-0.1560613607
GSE35957Up0.0445451317
GSE36640Up0.0672520132
GSE54402Down-0.1512845141
GSE9593Up0.1695446685
GSE43922Up0.0325005215
GSE24585Up0.0143472774
GSE37065Down-0.0741075075
GSE28863_A1Down-0.1512337434
GSE28863_A2Down-0.1251449792
GSE28863_A3Up0.3938511247
GSE28863_A4Up0.1985327422
GSE48662Up0.0017689918

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

LesinuradDB11560 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.