HCSGD entry for MMP21
1. General information
| Official gene symbol | MMP21 |
|---|---|
| Entrez ID | 118856 |
| Gene full name | matrix metallopeptidase 21 |
| Other gene symbols | MMP-21 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0031012 | Extracellular matrix | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2533387789 | 0.9379215911 | 0.9430750141 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2264387641 |
| GSE13712_SHEAR | Up | 0.2111727016 |
| GSE13712_STATIC | Down | -0.0746440354 |
| GSE19018 | Up | 0.0547293017 |
| GSE19899_A1 | Up | 0.0792334625 |
| GSE19899_A2 | Up | 0.1300288523 |
| PubMed_21979375_A1 | Up | 0.1475785277 |
| PubMed_21979375_A2 | Up | 0.1638095410 |
| GSE35957 | Up | 0.2629314210 |
| GSE36640 | Down | -0.0156381620 |
| GSE54402 | Up | 0.2628199331 |
| GSE9593 | Down | -0.1789333311 |
| GSE43922 | Up | 0.1092844539 |
| GSE24585 | Down | -0.0456921920 |
| GSE37065 | Down | -0.0710196500 |
| GSE28863_A1 | Down | -0.0207299749 |
| GSE28863_A2 | Down | -0.0191554030 |
| GSE28863_A3 | Up | 0.3717059061 |
| GSE28863_A4 | Up | 0.0770422003 |
| GSE48662 | Up | 0.0083619899 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Marimastat | DB00786 | APRD00559 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
