HCSGD entry for DEGS2
1. General information
| Official gene symbol | DEGS2 |
|---|---|
| Entrez ID | 123099 |
| Gene full name | delta(4)-desaturase, sphingolipid 2 |
| Other gene symbols | C14orf66 DES2 FADS8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000170 | Sphingosine hydroxylase activity | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006633 | Fatty acid biosynthetic process | IEA | biological_process |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0006667 | Sphinganine metabolic process | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016705 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEA | molecular_function |
| GO:0030148 | Sphingolipid biosynthetic process | TAS | biological_process |
| GO:0042284 | Sphingolipid delta-4 desaturase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046513 | Ceramide biosynthetic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2608218685 | 0.7337653661 | 0.9540150639 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0377432792 |
| GSE13712_SHEAR | Up | 0.2021739082 |
| GSE13712_STATIC | Up | 0.0128168477 |
| GSE19018 | Up | 0.4373874883 |
| GSE19899_A1 | Down | -0.0118982450 |
| GSE19899_A2 | Up | 0.3238427381 |
| PubMed_21979375_A1 | Down | -0.4907961675 |
| PubMed_21979375_A2 | Down | -0.1814293810 |
| GSE35957 | Down | -0.0983342732 |
| GSE36640 | Down | -0.1567423819 |
| GSE54402 | Down | -0.0799998943 |
| GSE9593 | Down | -0.0116187017 |
| GSE43922 | Up | 0.1507254577 |
| GSE24585 | Up | 0.6597417612 |
| GSE37065 | Down | -0.0459290853 |
| GSE28863_A1 | Down | -0.0130651112 |
| GSE28863_A2 | Down | -0.0444087970 |
| GSE28863_A3 | Up | 0.3443242268 |
| GSE28863_A4 | Down | -0.0482773566 |
| GSE48662 | Down | -0.0203222463 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
