HCSGD entry for DMBX1

1. General information

Official gene symbolDMBX1
Entrez ID127343
Gene full namediencephalon/mesencephalon homeobox 1
Other gene symbolsMBX OTX3 PAXB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0003677DNA bindingISSmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityISSmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007417Central nervous system developmentISSbiological_process
GO:0007420Brain developmentISSbiological_process
GO:0008343Adult feeding behaviorIEAbiological_process
GO:0008344Adult locomotory behaviorIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0043565Sequence-specific DNA bindingISSmolecular_function
GO:0045892Negative regulation of transcription, DNA-templatedISSbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0048589Developmental growthISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.46201270850.85417533150.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1372614153
GSE13712_SHEARDown-0.0256794937
GSE13712_STATICDown-0.1202191539
GSE19018Up0.0023116848
GSE19899_A1Up0.1564103325
GSE19899_A2Down-0.2163659306
PubMed_21979375_A1Up0.1683932462
PubMed_21979375_A2Up0.1460212172
GSE35957Up0.2961589396
GSE36640Down-0.1353331409
GSE54402Down-0.1728003647
GSE9593Down-0.0131393963
GSE43922Up0.0507729231
GSE24585Down-0.0260171397
GSE37065Up0.0049643339
GSE28863_A1Up0.0394353032
GSE28863_A2Up0.2099383771
GSE28863_A3Up0.0851766424
GSE28863_A4Up0.1425743714
GSE48662Down-0.0323936175

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017349MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.