HCSGD entry for UHMK1
1. General information
| Official gene symbol | UHMK1 |
|---|---|
| Entrez ID | 127933 |
| Gene full name | U2AF homology motif (UHM) kinase 1 |
| Other gene symbols | KIS KIST P-CIP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IC | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0007050 | Cell cycle arrest | IMP | biological_process |
| GO:0016740 | Transferase activity | IC | molecular_function |
| GO:0018105 | Peptidyl-serine phosphorylation | IDA ISS | biological_process |
| GO:0019899 | Enzyme binding | IEA | molecular_function |
| GO:0030424 | Axon | ISS | cellular_component |
| GO:0031175 | Neuron projection development | ISS | biological_process |
| GO:0032839 | Dendrite cytoplasm | ISS | cellular_component |
| GO:0043021 | Ribonucleoprotein complex binding | ISS | molecular_function |
| GO:0045948 | Positive regulation of translational initiation | ISS | biological_process |
| GO:0046777 | Protein autophosphorylation | IDA | biological_process |
| GO:0046825 | Regulation of protein export from nucleus | IDA | biological_process |
| GO:0071598 | Neuronal ribonucleoprotein granule | ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0918890202 | 0.8180542609 | 0.6376511732 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1671866826 |
| GSE13712_SHEAR | Up | 0.4834678679 |
| GSE13712_STATIC | Up | 0.2882952067 |
| GSE19018 | Up | 0.1746704904 |
| GSE19899_A1 | Down | -0.0038451331 |
| GSE19899_A2 | Down | -0.0539680699 |
| PubMed_21979375_A1 | Down | -0.1222931692 |
| PubMed_21979375_A2 | Up | 0.5088808458 |
| GSE35957 | Up | 0.2368378324 |
| GSE36640 | Up | 0.2347455013 |
| GSE54402 | Up | 0.1733797226 |
| GSE9593 | Up | 0.2658875751 |
| GSE43922 | Up | 0.0637658313 |
| GSE24585 | Up | 0.0775260861 |
| GSE37065 | Down | -0.0306963897 |
| GSE28863_A1 | Down | -0.2799018808 |
| GSE28863_A2 | Up | 0.3432941935 |
| GSE28863_A3 | Down | -0.7348243091 |
| GSE28863_A4 | Up | 0.0164600215 |
| GSE48662 | Up | 0.2265512003 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT002824 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT002824 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT004890 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT004890 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017233 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019310 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021385 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-503-5p | MIMAT0002874 | MIRT041113 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-185-5p | MIMAT0000455 | MIRT045366 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
