HCSGD entry for CREM

1. General information

Official gene symbolCREM
Entrez ID1390
Gene full namecAMP responsive element modulator
Other gene symbolsCREM-2 ICER hCREM-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEA NASmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEA NAScellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIDA NASbiological_process
GO:0006687Glycosphingolipid metabolic processIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0008140CAMP response element binding protein bindingNASmolecular_function
GO:0030154Cell differentiationIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06303898790.56897202610.54299638671.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3123457550
GSE13712_SHEARUp0.4616165222
GSE13712_STATICUp0.6033787165
GSE19018Down-0.0799015524
GSE19899_A1Up0.1080577816
GSE19899_A2Up0.4328796787
PubMed_21979375_A1Up1.8264902644
PubMed_21979375_A2Up0.3652095204
GSE35957Down-0.1749459273
GSE36640Down-0.0567661740
GSE54402Up0.4024315749
GSE9593Down-0.1759957428
GSE43922Up0.5099662868
GSE24585Down-0.2605221578
GSE37065Up0.3028239741
GSE28863_A1Down-0.0098618043
GSE28863_A2Down-0.1134020401
GSE28863_A3Down-0.3666739476
GSE28863_A4Down-0.0432628832
GSE48662Down-0.3237624250

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.