HCSGD entry for MYL6B

1. General information

Official gene symbolMYL6B
Entrez ID140465
Gene full namemyosin, light chain 6B, alkali, smooth muscle and non-muscle
Other gene symbolsMLC1SA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003774Motor activityTASmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0005859Muscle myosin complexTAScellular_component
GO:0006936Muscle contractionTASbiological_process
GO:0007519Skeletal muscle tissue developmentTASbiological_process
GO:0008152Metabolic processTASbiological_process
GO:0008307Structural constituent of muscleTASmolecular_function
GO:0016459Myosin complexTAScellular_component
GO:0016461Unconventional myosin complexTAScellular_component
GO:0030049Muscle filament slidingTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98219177460.01599842330.99999024730.2465391228

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0456037005
GSE13712_SHEARDown-0.6530798149
GSE13712_STATICDown-0.5352621237
GSE19018Up0.2080916934
GSE19899_A1Down-0.6643995023
GSE19899_A2Down-0.5373675498
PubMed_21979375_A1Down-0.1821386144
PubMed_21979375_A2Down-0.7338881155
GSE35957Down-0.6692785535
GSE36640Down-0.4729322268
GSE54402Up0.1411064891
GSE9593Down-0.2129488790
GSE43922Down-0.0072597852
GSE24585Up0.1715754617
GSE37065Down-0.1431671002
GSE28863_A1Down-0.4298732962
GSE28863_A2Down-0.6990048195
GSE28863_A3Up0.0481228128
GSE28863_A4Up0.1339961397
GSE48662Down-0.0566288276

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACIDDB08378 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.