HCSGD entry for CTBP2
1. General information
| Official gene symbol | CTBP2 |
|---|---|
| Entrez ID | 1488 |
| Gene full name | C-terminal binding protein 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003714 | Transcription corepressor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | ISS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | TAS | biological_process |
| GO:0016616 | Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | IEA | molecular_function |
| GO:0017053 | Transcriptional repressor complex | ISS | cellular_component |
| GO:0019079 | Viral genome replication | TAS | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0045202 | Synapse | IEA | cellular_component |
| GO:0045892 | Negative regulation of transcription, DNA-templated | ISS | biological_process |
| GO:0050872 | White fat cell differentiation | ISS | biological_process |
| GO:0051287 | NAD binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8953965731 | 0.1740496144 | 0.9999902473 | 0.8075928811 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0105074146 |
| GSE13712_SHEAR | Up | 0.0616920315 |
| GSE13712_STATIC | Down | -0.2423198780 |
| GSE19018 | Up | 0.5057254531 |
| GSE19899_A1 | Down | -0.4453860335 |
| GSE19899_A2 | Down | -0.1368243911 |
| PubMed_21979375_A1 | Up | 0.1744833055 |
| PubMed_21979375_A2 | Down | -0.2738707661 |
| GSE35957 | Down | -0.4256828489 |
| GSE36640 | Down | -0.6051770612 |
| GSE54402 | Down | -0.1416002725 |
| GSE9593 | Down | -0.0304570513 |
| GSE43922 | Down | -0.1205690126 |
| GSE24585 | Down | -0.0013864791 |
| GSE37065 | Down | -0.1908151685 |
| GSE28863_A1 | Up | 0.2932826226 |
| GSE28863_A2 | Up | 0.1379940419 |
| GSE28863_A3 | Down | -0.1144523767 |
| GSE28863_A4 | Up | 0.0241895794 |
| GSE48662 | Up | 0.0269305603 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023997 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051934 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
