HCSGD entry for CTSL2

1. General information

Official gene symbolCTSL2
Entrez ID1515
Gene full namecathepsin L2
Other gene symbolsCATL2 CTSU CTSV
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004177Aminopeptidase activityIEAmolecular_function
GO:0004197Cysteine-type endopeptidase activityIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005902MicrovillusIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0008234Cysteine-type peptidase activityTASmolecular_function
GO:0009267Cellular response to starvationIEAbiological_process
GO:0009749Response to glucoseIEAbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0010259Multicellular organismal agingIEAbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0021675Nerve developmentIEAbiological_process
GO:0022617Extracellular matrix disassemblyTASbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0030984Kininogen bindingIEAmolecular_function
GO:0032403Protein complex bindingIEAmolecular_function
GO:0034698Response to gonadotropinIEAbiological_process
GO:0042277Peptide bindingIEAmolecular_function
GO:0043005Neuron projectionIEAcellular_component
GO:0043202Lysosomal lumenTAScellular_component
GO:0043204PerikaryonIEAcellular_component
GO:0046697DecidualizationIEAbiological_process
GO:0048102Autophagic cell deathIEAbiological_process
GO:0051384Response to glucocorticoidIEAbiological_process
GO:0060008Sertoli cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.25311384830.54879076020.94274063381.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1538682571
GSE13712_SHEARUp0.0377585848
GSE13712_STATICDown-0.4359175610
GSE19018Down-0.0191456796
GSE19899_A1Up0.1077200966
GSE19899_A2Down-0.2245995105
PubMed_21979375_A1Up0.2617310379
PubMed_21979375_A2Up0.0427815862
GSE35957Down-0.4048847300
GSE36640Down-0.3426207146
GSE54402Down-0.1038680455
GSE9593Up0.6044086521
GSE43922Up0.0153112603
GSE24585Up1.8639525116
GSE37065Down-0.1204692247
GSE28863_A1Down-0.0266043810
GSE28863_A2Up0.1176595960
GSE28863_A3Up0.1906662356
GSE28863_A4Down-0.0953611945
GSE48662Down-0.1954050334

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

3-amino-5-phenylpentaneDB02869 EXPT02332
4-Methylpiperazin-1-Yl Carbonyl GroupDB04451 EXPT02419

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029699MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.