HCSGD entry for CREBRF
1. General information
| Official gene symbol | CREBRF |
|---|---|
| Entrez ID | 153222 |
| Gene full name | CREB3 regulatory factor |
| Other gene symbols | C5orf41 LRF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0006986 | Response to unfolded protein | IEA | biological_process |
| GO:0016604 | Nuclear body | IDA | cellular_component |
| GO:0032388 | Positive regulation of intracellular transport | IDA | biological_process |
| GO:0034976 | Response to endoplasmic reticulum stress | IDA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045732 | Positive regulation of protein catabolic process | IDA | biological_process |
| GO:0051222 | Positive regulation of protein transport | IDA | biological_process |
| GO:1900102 | Negative regulation of endoplasmic reticulum unfolded protein response | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0055811481 | 0.4921208047 | 0.1968539491 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4162892815 |
| GSE13712_SHEAR | Down | -0.0775259866 |
| GSE13712_STATIC | Down | -0.2142240149 |
| GSE19018 | Up | 0.7724600088 |
| GSE19899_A1 | Up | 0.1112005129 |
| GSE19899_A2 | Up | 0.3987747653 |
| PubMed_21979375_A1 | Down | -0.0156001877 |
| PubMed_21979375_A2 | Up | 0.7205580070 |
| GSE35957 | Up | 0.6890727794 |
| GSE36640 | Up | 2.0563749012 |
| GSE54402 | Down | -0.1230427310 |
| GSE9593 | Up | 0.8609614833 |
| GSE43922 | Down | -0.2832269481 |
| GSE24585 | Up | 0.8559190277 |
| GSE37065 | Up | 0.5768927284 |
| GSE28863_A1 | Up | 0.1097235133 |
| GSE28863_A2 | Up | 0.3477206736 |
| GSE28863_A3 | Down | -0.8437110406 |
| GSE28863_A4 | Down | -0.6955485585 |
| GSE48662 | Up | 0.7440095666 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT005103 | Microarray | Functional MTI (Weak) | 19193853 |
| hsa-miR-421 | MIMAT0003339 | MIRT016126 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017940 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028082 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-484 | MIMAT0002174 | MIRT042350 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045087 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
