HCSGD entry for DBP
1. General information
| Official gene symbol | DBP |
|---|---|
| Entrez ID | 1628 |
| Gene full name | D site of albumin promoter (albumin D-box) binding protein |
| Other gene symbols | DABP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IDA | molecular_function |
| GO:0001077 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | IDA IEA | molecular_function |
| GO:0001889 | Liver development | IEA | biological_process |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0048511 | Rhythmic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6903868926 | 0.3996014931 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1503049760 |
| GSE13712_SHEAR | Down | -0.2361337306 |
| GSE13712_STATIC | Down | -0.1995915980 |
| GSE19018 | Up | 0.1587703273 |
| GSE19899_A1 | Up | 0.0230095347 |
| GSE19899_A2 | Down | -0.1529011757 |
| PubMed_21979375_A1 | Down | -0.0479531957 |
| PubMed_21979375_A2 | Down | -0.1544260219 |
| GSE35957 | Down | -0.0974710111 |
| GSE36640 | Up | 0.1415119866 |
| GSE54402 | Down | -0.3216330679 |
| GSE9593 | Up | 0.1208215152 |
| GSE43922 | Down | -0.0890560770 |
| GSE24585 | Up | 0.1931167514 |
| GSE37065 | Up | 0.1377074576 |
| GSE28863_A1 | Up | 0.1762890218 |
| GSE28863_A2 | Up | 0.1836172533 |
| GSE28863_A3 | Up | 0.1903123900 |
| GSE28863_A4 | Down | -0.0965031629 |
| GSE48662 | Up | 0.1202197361 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 3 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26464516 | Human genetic studies revealed significant associations of PDE1A single nucleotide polymorphisms with diastolic blood pressure (DBP; beta=0 |
| 19484468 | However, pCMBS, which inhibits AQP1, the major water exchange pathway, inhibited flickering in all cells, and yet it was restored by the membrane intercalating species dibutyl phthalate (DBP) |
| 10092208 | Analysis of the expression of relevant hepatic genes by reverse Northern and semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR) revealed that culturing hepatocytes in collagen gels results in a sustained higher expression of key liver transcription factor genes DBP, C/EBP-alpha and -beta, and HNF-1 and -4, as well as specific liver enzyme genes (phosphoenol pyryvate carboxykinase, and carbamoylphosphate-synthetase I) |
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