HCSGD entry for DDC

1. General information

Official gene symbolDDC
Entrez ID1644
Gene full namedopa decarboxylase (aromatic L-amino acid decarboxylase)
Other gene symbolsAADC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004058Aromatic-L-amino-acid decarboxylase activityIDA IEA TASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0006520Cellular amino acid metabolic processIEAbiological_process
GO:0007623Circadian rhythmIEAbiological_process
GO:0008021Synaptic vesicleIEAcellular_component
GO:0010259Multicellular organismal agingIEAbiological_process
GO:0015842Synaptic vesicle amine transportIEAbiological_process
GO:0016597Amino acid bindingIEAmolecular_function
GO:0016831Carboxy-lyase activityIEAmolecular_function
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0030170Pyridoxal phosphate bindingIEAmolecular_function
GO:0030424AxonIEAcellular_component
GO:0033076Isoquinoline alkaloid metabolic processIEAbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0035690Cellular response to drugIEAbiological_process
GO:0042416Dopamine biosynthetic processIEAbiological_process
GO:0042423Catecholamine biosynthetic processTASbiological_process
GO:0042427Serotonin biosynthetic processIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046219Indolalkylamine biosynthetic processTASbiological_process
GO:0046684Response to pyrethroidIEAbiological_process
GO:0052314Phytoalexin metabolic processIEAbiological_process
GO:0071312Cellular response to alkaloidIEAbiological_process
GO:0071363Cellular response to growth factor stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59440552790.89157042290.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2368117998
GSE13712_SHEARUp0.0570156408
GSE13712_STATICDown-0.0885811378
GSE19018Down-0.0595321445
GSE19899_A1Up0.1321556637
GSE19899_A2Up0.0702857982
PubMed_21979375_A1Up0.1970319805
PubMed_21979375_A2Up0.1374840076
GSE35957Up0.0521111632
GSE36640Up0.0626982865
GSE54402Up0.0068415030
GSE9593Up0.0014144325
GSE43922Up0.0140074274
GSE24585Up0.0050720390
GSE37065Up0.0343286121
GSE28863_A1Down-0.0938446024
GSE28863_A2Down-0.0857825327
GSE28863_A3Up0.1814515123
GSE28863_A4Up0.0829035515
GSE48662Down-0.1059227758

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

CHF-1512DB05307 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.