HCSGD entry for DACT2
1. General information
| Official gene symbol | DACT2 |
|---|---|
| Entrez ID | 168002 |
| Gene full name | dishevelled-binding antagonist of beta-catenin 2 |
| Other gene symbols | C6orf116 DAPPER2 DPR2 RP11-503C24.7 bA503C24.7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003382 | Epithelial cell morphogenesis | ISS | biological_process |
| GO:0005080 | Protein kinase C binding | ISS | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0007162 | Negative regulation of cell adhesion | ISS | biological_process |
| GO:0008013 | Beta-catenin binding | ISS | molecular_function |
| GO:0008134 | Transcription factor binding | ISS | molecular_function |
| GO:0043588 | Skin development | ISS | biological_process |
| GO:0051018 | Protein kinase A binding | ISS | molecular_function |
| GO:0070097 | Delta-catenin binding | ISS | molecular_function |
| GO:0072061 | Inner medullary collecting duct development | ISS | biological_process |
| GO:1900108 | Negative regulation of nodal signaling pathway | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4052712207 | 0.7957981726 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0055179923 |
| GSE13712_SHEAR | Down | -0.0016048076 |
| GSE13712_STATIC | Down | -0.0303411895 |
| GSE19018 | Up | 0.0795549361 |
| GSE19899_A1 | Up | 0.1465333822 |
| GSE19899_A2 | Up | 0.1844132549 |
| PubMed_21979375_A1 | Down | -0.3213558880 |
| PubMed_21979375_A2 | Down | -0.1680894463 |
| GSE35957 | Down | -0.0057510529 |
| GSE36640 | Up | 0.0391981920 |
| GSE54402 | Up | 0.1487252950 |
| GSE9593 | Down | -0.1569284849 |
| GSE43922 | Up | 0.1096828359 |
| GSE24585 | Up | 0.1935399904 |
| GSE37065 | Down | -0.2419243398 |
| GSE28863_A1 | Down | -0.0569001048 |
| GSE28863_A2 | Up | 0.1505892672 |
| GSE28863_A3 | Up | 0.3956502808 |
| GSE28863_A4 | Up | 0.1422683084 |
| GSE48662 | Up | 0.0442990371 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT022027 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041542 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
