HCSGD entry for DLG1

1. General information

Official gene symbolDLG1
Entrez ID1739
Gene full namediscs, large homolog 1 (Drosophila)
Other gene symbolsDLGH1 SAP-97 SAP97 dJ1061C18.1.1 hdlg
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001658Branching involved in ureteric bud morphogenesisIEAbiological_process
GO:0001771Immunological synapse formationIEAbiological_process
GO:0001772Immunological synapseIEA TAScellular_component
GO:0001935Endothelial cell proliferationIDAbiological_process
GO:0002088Lens development in camera-type eyeIEAbiological_process
GO:0002369T cell cytokine productionIEAbiological_process
GO:0004385Guanylate kinase activityTASmolecular_function
GO:0004721Phosphoprotein phosphatase activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005874MicrotubuleIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005911Cell-cell junctionIDAcellular_component
GO:0005923Tight junctionIDAcellular_component
GO:0007015Actin filament organizationIDAbiological_process
GO:0007093Mitotic cell cycle checkpointNASbiological_process
GO:0007163Establishment or maintenance of cell polarityTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008022Protein C-terminus bindingIPImolecular_function
GO:0008092Cytoskeletal protein bindingTASmolecular_function
GO:0008104Protein localizationIEAbiological_process
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0009898Cytoplasmic side of plasma membraneIDAcellular_component
GO:0014069Postsynaptic densityIEAcellular_component
GO:0014704Intercalated discTAScellular_component
GO:0015459Potassium channel regulator activityIDA NASmolecular_function
GO:0016032Viral processIEAbiological_process
GO:0016310PhosphorylationTASbiological_process
GO:0016311DephosphorylationTASbiological_process
GO:0016323Basolateral plasma membraneIDAcellular_component
GO:0016328Lateral plasma membraneIEAcellular_component
GO:0016337Cell-cell adhesionIDAbiological_process
GO:0019901Protein kinase bindingIPImolecular_function
GO:0019902Phosphatase bindingIPImolecular_function
GO:0030054Cell junctionIDA IEAcellular_component
GO:0030432PeristalsisIEAbiological_process
GO:0030838Positive regulation of actin filament polymerizationIEAbiological_process
GO:0030866Cortical actin cytoskeleton organizationIDAbiological_process
GO:0031253Cell projection membraneIEAcellular_component
GO:0031434Mitogen-activated protein kinase kinase bindingIPImolecular_function
GO:0031579Membrane raft organizationIEAbiological_process
GO:0031594Neuromuscular junctionIEAcellular_component
GO:0032147Activation of protein kinase activityIEAbiological_process
GO:0032947Protein complex scaffoldIEAmolecular_function
GO:0033268Node of RanvierIEAcellular_component
GO:0035748Myelin sheath abaxonal regionIEAcellular_component
GO:0042110T cell activationIEAbiological_process
GO:0042130Negative regulation of T cell proliferationIEAbiological_process
GO:0042383SarcolemmaIEAcellular_component
GO:0042391Regulation of membrane potentialIDA IEAbiological_process
GO:0042982Amyloid precursor protein metabolic processIEAbiological_process
GO:0043219Lateral loopIEAcellular_component
GO:0043268Positive regulation of potassium ion transportIDAbiological_process
GO:0044325Ion channel bindingIPImolecular_function
GO:0045121Membrane raftIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0045930Negative regulation of mitotic cell cycleIMPbiological_process
GO:0046939Nucleotide phosphorylationTASbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0048608Reproductive structure developmentIEAbiological_process
GO:0048704Embryonic skeletal system morphogenesisIEAbiological_process
GO:0048745Smooth muscle tissue developmentIEAbiological_process
GO:0050680Negative regulation of epithelial cell proliferationIEAbiological_process
GO:0060022Hard palate developmentIEAbiological_process
GO:0070830Tight junction assemblyIDAbiological_process
GO:0072659Protein localization to plasma membraneIMP TASbiological_process
GO:0090004Positive regulation of establishment of protein localization to plasma membraneIDAbiological_process
GO:0097016L27 domain bindingIPImolecular_function
GO:0097025MPP7-DLG1-LIN7 complexIDAcellular_component
GO:1902305Regulation of sodium ion transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.60986851560.42797843930.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2340940506
GSE13712_SHEARUp0.1489354945
GSE13712_STATICUp0.1200728324
GSE19018Up0.1753413802
GSE19899_A1Down-0.0789504661
GSE19899_A2Down-0.3597177700
PubMed_21979375_A1Up0.1733606231
PubMed_21979375_A2Down-0.1404210103
GSE35957Down-0.2124757498
GSE36640Down-0.2956045293
GSE54402Down-0.0021456714
GSE9593Up0.1336458615
GSE43922Down-0.0573823022
GSE24585Up0.1972258880
GSE37065Up0.1242208634
GSE28863_A1Up0.2282457605
GSE28863_A2Up0.2082320128
GSE28863_A3Down-0.0264933689
GSE28863_A4Down-0.1965749942
GSE48662Up0.1906792717

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-21-5pMIMAT0000076MIRT030999MicroarrayFunctional MTI (Weak)18591254
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.