HCSGD entry for DNASE1L1
1. General information
| Official gene symbol | DNASE1L1 |
|---|---|
| Entrez ID | 1774 |
| Gene full name | deoxyribonuclease I-like 1 |
| Other gene symbols | DNAS1L1 DNASEX DNL1L G4.8 XIB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0004536 | Deoxyribonuclease activity | IEA TAS | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0006259 | DNA metabolic process | TAS | biological_process |
| GO:0016888 | Endodeoxyribonuclease activity, producing 5'-phosphomonoesters | IEA | molecular_function |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0015440979 | 0.7585957676 | 0.1052906736 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2846523511 |
| GSE13712_SHEAR | Up | 0.2661104306 |
| GSE13712_STATIC | Up | 0.6863702058 |
| GSE19018 | Up | 1.8362419687 |
| GSE19899_A1 | Up | 0.6836050009 |
| GSE19899_A2 | Up | 1.0601852708 |
| PubMed_21979375_A1 | Down | -0.9748737122 |
| PubMed_21979375_A2 | Up | 0.3126669160 |
| GSE35957 | Down | -0.5887332706 |
| GSE36640 | Up | 2.1900548248 |
| GSE54402 | Down | -0.3670965741 |
| GSE9593 | Up | 0.8072229793 |
| GSE43922 | Up | 0.1280035067 |
| GSE24585 | Up | 0.7574076969 |
| GSE37065 | Up | 0.1117434244 |
| GSE28863_A1 | Up | 0.4909753294 |
| GSE28863_A2 | Down | -0.5148929524 |
| GSE28863_A3 | Up | 0.0830713524 |
| GSE28863_A4 | Down | -0.1071771521 |
| GSE48662 | Up | 0.2038490182 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT042294 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
