HCSGD entry for DPYSL2
1. General information
| Official gene symbol | DPYSL2 |
|---|---|
| Entrez ID | 1808 |
| Gene full name | dihydropyrimidinase-like 2 |
| Other gene symbols | CRMP-2 CRMP2 DHPRP2 DRP-2 DRP2 N2A3 ULIP-2 ULIP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001975 | Response to amphetamine | IEA | biological_process |
| GO:0004157 | Dihydropyrimidinase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0005874 | Microtubule | IDA | cellular_component |
| GO:0006139 | Nucleobase-containing compound metabolic process | TAS | biological_process |
| GO:0006208 | Pyrimidine nucleobase catabolic process | IEA | biological_process |
| GO:0006897 | Endocytosis | IMP | biological_process |
| GO:0007010 | Cytoskeleton organization | ISS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007399 | Nervous system development | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0014049 | Positive regulation of glutamate secretion | IEA | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016810 | Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | IEA | molecular_function |
| GO:0019901 | Protein kinase binding | IEA | molecular_function |
| GO:0021510 | Spinal cord development | IEA | biological_process |
| GO:0021772 | Olfactory bulb development | IEA | biological_process |
| GO:0030424 | Axon | IEA | cellular_component |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0030426 | Growth cone | IEA | cellular_component |
| GO:0042220 | Response to cocaine | IEA | biological_process |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0045664 | Regulation of neuron differentiation | IEA | biological_process |
| GO:0048489 | Synaptic vesicle transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8622938262 | 0.0110036017 | 0.9999902473 | 0.2076170609 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5233987088 |
| GSE13712_SHEAR | Up | 0.0656918552 |
| GSE13712_STATIC | Down | -0.4717695583 |
| GSE19018 | Up | 0.0928846976 |
| GSE19899_A1 | Down | -0.6826711824 |
| GSE19899_A2 | Down | -0.7212977949 |
| PubMed_21979375_A1 | Down | -0.8048903608 |
| PubMed_21979375_A2 | Down | -0.6257506281 |
| GSE35957 | Up | 0.5831237556 |
| GSE36640 | Down | -0.1788650094 |
| GSE54402 | Down | -0.7311365529 |
| GSE9593 | Up | 0.4621419340 |
| GSE43922 | Down | -1.0901163394 |
| GSE24585 | Down | -0.3481819549 |
| GSE37065 | Down | -0.0942230028 |
| GSE28863_A1 | Up | 0.5490026667 |
| GSE28863_A2 | Up | 0.6149543461 |
| GSE28863_A3 | Down | -0.4242108983 |
| GSE28863_A4 | Down | -0.2974374599 |
| GSE48662 | Up | 0.0837872276 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-19a-3p | MIMAT0000073 | MIRT031306 | Reporter assay | Functional MTI | 21654684 |
| hsa-miR-425-5p | MIMAT0003393 | MIRT039304 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044587 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047721 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047866 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050956 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
