HCSGD entry for ECM1

1. General information

Official gene symbolECM1
Entrez ID1893
Gene full nameextracellular matrix protein 1
Other gene symbolsURBWD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001503OssificationIEAbiological_process
GO:0001525AngiogenesisIEAbiological_process
GO:0001938Positive regulation of endothelial cell proliferationIDAbiological_process
GO:0001960Negative regulation of cytokine-mediated signaling pathwayIEAbiological_process
GO:0002020Protease bindingIPImolecular_function
GO:0002828Regulation of type 2 immune responseIEAbiological_process
GO:0004871Signal transducer activityIMPmolecular_function
GO:0005134Interleukin-2 receptor bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005578Proteinaceous extracellular matrixNAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0007165Signal transductionIMPbiological_process
GO:0008022Protein C-terminus bindingIPImolecular_function
GO:0010466Negative regulation of peptidase activityIDAbiological_process
GO:0019899Enzyme bindingIPImolecular_function
GO:0030502Negative regulation of bone mineralizationIDAbiological_process
GO:0031012Extracellular matrixIDAcellular_component
GO:0031214Biomineral tissue developmentIEAbiological_process
GO:0043123Positive regulation of I-kappaB kinase/NF-kappaB signalingIMPbiological_process
GO:0043236Laminin bindingIPImolecular_function
GO:0045766Positive regulation of angiogenesisIDAbiological_process
GO:2000404Regulation of T cell migrationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00977085600.11502075910.25226323530.6495304441

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1752391074
GSE13712_SHEARDown-1.6868676142
GSE13712_STATICDown-2.1074660518
GSE19018Up1.9516863466
GSE19899_A1Up0.4401863564
GSE19899_A2Down-0.3392025567
PubMed_21979375_A1Down-0.2590094506
PubMed_21979375_A2Up1.4101331748
GSE35957Up0.6799434060
GSE36640Up1.2113924522
GSE54402Up0.1238853960
GSE9593Up0.7967762167
GSE43922Down-0.3068658691
GSE24585Up0.1079718603
GSE37065Up0.2326098257
GSE28863_A1Up0.0225830663
GSE28863_A2Up1.0315353473
GSE28863_A3Down-0.0323040273
GSE28863_A4Down-0.1306260717
GSE48662Up0.1095890792

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.