HCSGD entry for NLRC3


1. General information

Official gene symbolNLRC3
Entrez ID197358
Gene full nameNLR family, CARD domain containing 3
Other gene symbolsCLR16.2 NOD3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003674Molecular_functionNDmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0007249I-kappaB kinase/NF-kappaB signalingIDAbiological_process
GO:0031396Regulation of protein ubiquitinationIEAbiological_process
GO:0032088Negative regulation of NF-kappaB transcription factor activityIDAbiological_process
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0042110T cell activationIEPbiological_process
GO:0043124Negative regulation of I-kappaB kinase/NF-kappaB signalingIEA IMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.40230406900.40332243840.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0658898106
GSE13712_SHEARUp0.9171261955
GSE13712_STATICUp0.2467819176
GSE19018Down-0.0820870461
GSE19899_A1Up0.0527302666
GSE19899_A2Down-0.0245080221
PubMed_21979375_A1Down-0.5355369600
PubMed_21979375_A2Down-0.2775321634
GSE35957Up0.1112965576
GSE36640Up0.1145524736
GSE54402Up0.0079392747
GSE9593Down-0.1281470213
GSE43922Up0.1080308501
GSE24585Down-0.2088969889
GSE37065Down-0.0409903168
GSE28863_A1Down-0.2835510137
GSE28863_A2Down-0.3132518037
GSE28863_A3Up0.4169110048
GSE28863_A4Up0.1991695601
GSE48662Up0.0523455190

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.