HCSGD entry for SPRED2
1. General information
Official gene symbol | SPRED2 |
---|---|
Entrez ID | 200734 |
Gene full name | sprouty-related, EVH1 domain containing 2 |
Other gene symbols | Spred-2 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0000188 | Inactivation of MAPK activity | IEA ISS | biological_process |
GO:0005173 | Stem cell factor receptor binding | IEA ISS | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005886 | Plasma membrane | IEA | cellular_component |
GO:0007275 | Multicellular organismal development | IEA | biological_process |
GO:0009966 | Regulation of signal transduction | IEA | biological_process |
GO:0010801 | Negative regulation of peptidyl-threonine phosphorylation | IEA IMP | biological_process |
GO:0016020 | Membrane | IEA | cellular_component |
GO:0019901 | Protein kinase binding | IEA IPI | molecular_function |
GO:0030291 | Protein serine/threonine kinase inhibitor activity | IEA ISS | molecular_function |
GO:0030658 | Transport vesicle membrane | IEA | cellular_component |
GO:0031410 | Cytoplasmic vesicle | IEA | cellular_component |
GO:0043517 | Positive regulation of DNA damage response, signal transduction by p53 class mediator | IEA ISS | biological_process |
GO:0090311 | Regulation of protein deacetylation | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.0030300255 | 0.9904872801 | 0.1482403346 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Up | 0.1173428495 |
GSE13712_SHEAR | Up | 0.1586800218 |
GSE13712_STATIC | Up | 0.0548249640 |
GSE19018 | Up | 0.0988605240 |
GSE19899_A1 | Up | 0.8569823128 |
GSE19899_A2 | Up | 0.7464435779 |
PubMed_21979375_A1 | Up | 1.9924087947 |
PubMed_21979375_A2 | Up | 0.9224628433 |
GSE35957 | Up | 0.0156815934 |
GSE36640 | Up | 0.0871135087 |
GSE54402 | Up | 0.9142311223 |
GSE9593 | Up | 0.4134426184 |
GSE43922 | Up | 1.1262523733 |
GSE24585 | Up | 0.0112034660 |
GSE37065 | Down | -0.0265482542 |
GSE28863_A1 | Up | 0.4745358362 |
GSE28863_A2 | Up | 0.9287358885 |
GSE28863_A3 | Up | 0.1846622225 |
GSE28863_A4 | Down | -0.0309904707 |
GSE48662 | Down | -0.3609301245 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-186-5p | MIMAT0000456 | MIRT021167 | Sequencing | Functional MTI (Weak) | 20371350 |
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