HCSGD entry for SPRED2


1. General information

Official gene symbolSPRED2
Entrez ID200734
Gene full namesprouty-related, EVH1 domain containing 2
Other gene symbolsSpred-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000188Inactivation of MAPK activityIEA ISSbiological_process
GO:0005173Stem cell factor receptor bindingIEA ISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0009966Regulation of signal transductionIEAbiological_process
GO:0010801Negative regulation of peptidyl-threonine phosphorylationIEA IMPbiological_process
GO:0016020MembraneIEAcellular_component
GO:0019901Protein kinase bindingIEA IPImolecular_function
GO:0030291Protein serine/threonine kinase inhibitor activityIEA ISSmolecular_function
GO:0030658Transport vesicle membraneIEAcellular_component
GO:0031410Cytoplasmic vesicleIEAcellular_component
GO:0043517Positive regulation of DNA damage response, signal transduction by p53 class mediatorIEA ISSbiological_process
GO:0090311Regulation of protein deacetylationIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00303002550.99048728010.14824033461.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1173428495
GSE13712_SHEARUp0.1586800218
GSE13712_STATICUp0.0548249640
GSE19018Up0.0988605240
GSE19899_A1Up0.8569823128
GSE19899_A2Up0.7464435779
PubMed_21979375_A1Up1.9924087947
PubMed_21979375_A2Up0.9224628433
GSE35957Up0.0156815934
GSE36640Up0.0871135087
GSE54402Up0.9142311223
GSE9593Up0.4134426184
GSE43922Up1.1262523733
GSE24585Up0.0112034660
GSE37065Down-0.0265482542
GSE28863_A1Up0.4745358362
GSE28863_A2Up0.9287358885
GSE28863_A3Up0.1846622225
GSE28863_A4Down-0.0309904707
GSE48662Down-0.3609301245

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-186-5pMIMAT0000456MIRT021167SequencingFunctional MTI (Weak)20371350
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.