HCSGD entry for PDE12
1. General information
| Official gene symbol | PDE12 |
|---|---|
| Entrez ID | 201626 |
| Gene full name | phosphodiesterase 12 |
| Other gene symbols | 2'-PDE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004535 | Poly(A)-specific ribonuclease activity | IEA | molecular_function |
| GO:0005759 | Mitochondrial matrix | IEA | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2336083090 | 0.7471526766 | 0.9171980609 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1045996017 |
| GSE13712_SHEAR | Up | 0.2013915784 |
| GSE13712_STATIC | Up | 0.2378996545 |
| GSE19018 | Down | -0.6619409580 |
| GSE19899_A1 | Up | 0.2652753707 |
| GSE19899_A2 | Up | 0.4544370958 |
| PubMed_21979375_A1 | Up | 0.8202065787 |
| PubMed_21979375_A2 | Up | 0.4125283837 |
| GSE35957 | Down | -0.0515301383 |
| GSE36640 | Up | 0.1019399191 |
| GSE54402 | Up | 0.2024479522 |
| GSE9593 | Down | -0.0341743364 |
| GSE43922 | Up | 0.2468113823 |
| GSE24585 | Down | -0.4619174326 |
| GSE37065 | Up | 0.0550821028 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.2256509234 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT005039 | Microarray | Functional MTI (Weak) | 17699775 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT005039 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020694 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023732 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029374 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037032 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041882 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196b-5p | MIMAT0001080 | MIRT042666 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
