HCSGD entry for ALDH3A1

1. General information

Official gene symbolALDH3A1
Entrez ID218
Gene full namealdehyde dehydrogenase 3 family, member A1
Other gene symbolsALDH3 ALDHIII
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001666Response to hypoxiaIEAbiological_process
GO:00040283-chloroallyl aldehyde dehydrogenase activityIEAmolecular_function
GO:0004029Aldehyde dehydrogenase (NAD) activityIDAmolecular_function
GO:0004030Aldehyde dehydrogenase [NAD(P)+] activityIEAmolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005829CytosolIEA ISScellular_component
GO:0006081Cellular aldehyde metabolic processIDA IEAbiological_process
GO:0007568AgingIEAbiological_process
GO:0007584Response to nutrientIEAbiological_process
GO:0008106Alcohol dehydrogenase (NADP+) activityIDAmolecular_function
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0051384Response to glucocorticoidIEAbiological_process
GO:0051591Response to cAMPIEAbiological_process
GO:0055114Oxidation-reduction processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.29275155580.87774379390.99297856961.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1061060731
GSE13712_SHEARDown-0.0187610023
GSE13712_STATICUp0.0633378561
GSE19018Up0.0855532044
GSE19899_A1Up0.0058872305
GSE19899_A2Up0.3121001704
PubMed_21979375_A1Up0.1649005769
PubMed_21979375_A2Up0.0104274801
GSE35957Down-0.3924931153
GSE36640Down-0.0620463015
GSE54402Up0.0681053712
GSE9593Up1.0055655549
GSE43922Up0.0282956150
GSE24585Down-0.1723874836
GSE37065Up0.0580781087
GSE28863_A1Down-0.0326684375
GSE28863_A2Up0.0243521505
GSE28863_A3Up0.2693306270
GSE28863_A4Up0.1085109681
GSE48662Up0.2183236589

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-145-5pMIMAT0000437MIRT021523Reporter assay;MicroarrayFunctional MTI21351259
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.