HCSGD entry for BPTF
1. General information
| Official gene symbol | BPTF |
|---|---|
| Entrez ID | 2186 |
| Gene full name | bromodomain PHD finger transcription factor |
| Other gene symbols | FAC1 FALZ NURF301 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0001892 | Embryonic placenta development | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006200 | ATP catabolic process | IDA | biological_process |
| GO:0006338 | Chromatin remodeling | IDA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IMP | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IMP | biological_process |
| GO:0007420 | Brain development | IMP | biological_process |
| GO:0007492 | Endoderm development | IEA | biological_process |
| GO:0008094 | DNA-dependent ATPase activity | IDA | molecular_function |
| GO:0008134 | Transcription factor binding | IDA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
| GO:0016589 | NURF complex | IDA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IDA IMP | molecular_function |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1108311310 | 0.7192721477 | 0.6876469729 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1978338772 |
| GSE13712_SHEAR | Up | 0.6645211171 |
| GSE13712_STATIC | Up | 0.4713915426 |
| GSE19018 | Up | 0.0298446514 |
| GSE19899_A1 | Up | 0.3547704707 |
| GSE19899_A2 | Up | 0.0120297323 |
| PubMed_21979375_A1 | Up | 0.1407569171 |
| PubMed_21979375_A2 | Up | 0.2494534947 |
| GSE35957 | Down | -0.1329731351 |
| GSE36640 | Down | -0.1285381506 |
| GSE54402 | Up | 0.0078194313 |
| GSE9593 | Down | -0.0557019258 |
| GSE43922 | Up | 0.1237265609 |
| GSE24585 | Up | 0.4887660131 |
| GSE37065 | Down | -0.0146248540 |
| GSE28863_A1 | Down | -0.4163404866 |
| GSE28863_A2 | Down | -0.1604502852 |
| GSE28863_A3 | Up | 0.5106723133 |
| GSE28863_A4 | Up | 0.1126943968 |
| GSE48662 | Down | -0.2901071326 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018571 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036935 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037859 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-33b-5p | MIMAT0003301 | MIRT039578 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043685 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043889 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046732 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-204-5p | MIMAT0000265 | MIRT047009 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181b-5p | MIMAT0000257 | MIRT047286 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050239 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051824 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052582 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
