HCSGD entry for LNX2
1. General information
| Official gene symbol | LNX2 |
|---|---|
| Entrez ID | 222484 |
| Gene full name | ligand of numb-protein X 2 |
| Other gene symbols | PDZRN1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0030165 | PDZ domain binding | IEA | molecular_function |
| GO:0051260 | Protein homooligomerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1496327115 | 0.2515138141 | 0.7740416536 | 0.9630801745 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1237943297 |
| GSE13712_SHEAR | Up | 0.0569765873 |
| GSE13712_STATIC | Up | 0.1860072303 |
| GSE19018 | Down | -0.4480895079 |
| GSE19899_A1 | Up | 0.1830927426 |
| GSE19899_A2 | Down | -0.3092130300 |
| PubMed_21979375_A1 | Up | 0.9851841135 |
| PubMed_21979375_A2 | Up | 0.6145127002 |
| GSE35957 | Down | -0.4871045107 |
| GSE36640 | Up | 0.1940310307 |
| GSE54402 | Up | 0.6077369823 |
| GSE9593 | Down | -0.1382734091 |
| GSE43922 | Up | 0.3759995959 |
| GSE24585 | Up | 0.3655513125 |
| GSE37065 | Down | -0.2512278312 |
| GSE28863_A1 | Down | -0.0346785987 |
| GSE28863_A2 | Down | -0.1711642640 |
| GSE28863_A3 | Down | -0.8473121707 |
| GSE28863_A4 | Up | 0.0592201169 |
| GSE48662 | Down | -0.5385527079 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020558 | Reporter assay;Other | Functional MTI | 20584899 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022212 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
